- Highest batting average: Ty Cobb, .367
- Most singles: Pete Rose, 3,215
- Most doubles: Tris Speaker, 792
- Most triples: Sam Crawford, 309
- Most home runs: Barry Bonds, 762
- Most inside the park home runs: Jesse Burkett, 55
- Most home run by pitchers, Wes Ferrell, 38
- Most RBIs: Hank Aaron, 2,297
- Most hits: Pete Rose, 4,256
- Most runs scored: Rickey Henderson, 2,295
- Highest on-base percentage: Ted Williams, .482
- Most stolen bases: Rickey Henderson, 1,406
- Most steals of home: Ty Cobb, 54
- Highest slugging percentage: Babe Ruth, .690
- Highest OPS: Babe Ruth, 1.164
- Most walks: Barry Bonds, 2,553
- Most intentional walks: Barry Bonds, 686
- Most strikeouts: Reggie Jackson, 2,597
- Most at-bats: Pete Rose, 14,053
- Most total bases: Hank Aaron, 6,856
- Most runs created: Babe Ruth, 2,757
- Most games played: Pete Rose, 3,562